mtDNA Heteroplasmy: Origin, Detection, Significance, and Evolutionary Consequences
نویسندگان
چکیده
منابع مشابه
Parallelism, It's Evolutionary Origin and Systematic Significance
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Mitochondrial disease is a multifactorial disorder involving both nuclear and mitochondrial genomes. Over the past 20 years, great progress was achieved in the field of gene editing which raised the possibility of partial or complete elimination of mutant mtDNA that causes disease phenotypes. Each cell contains thousands of copies of mtDNA which can be either wild-type (WT) or mutant, a conditi...
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ژورنال
عنوان ژورنال: Life
سال: 2021
ISSN: 2075-1729
DOI: 10.3390/life11070633